“Will Sam and/or Castiel be put in a position where they have no choice but to kill, or try to kill, Dean?”
Ugh, no! (At least not Sam.)
cheryl42: “Catiel and Sam won't let that happen no matter the cost. Either kill Dean or make a sacrifice to save him.”
Alice: “I suspect that Sam and Castiel are going to try and kill him and fail.”
What’s with the suggestions that Sam tries to kill Dean? Even Dean doesn’t think Sam would be willing to go that far. If Sam tried to kill his brother, it would ruin the show and I don’t think that’s an exaggeration.